Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 10/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.51 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | PTPRB | P23467 | 2/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | EPM2A | O95278 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396750 | 0.93 | PTPN1 (0.49) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL14593120 | 0.93 | PTPN1 (0.52) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL5399280 | 0.91 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL5396785 | 0.90 | PTPN1 (0.54) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL14593188 | 0.89 | PTPN1 (0.50) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL5468252 | 0.86 | PTPN1 (0.57) | PTPN1PTPN2PTPN6PTPRC | |
| SCHEMBL5404409 | 0.86 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL5395213 | 0.86 | PTPN1 (0.50) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL14593187 | 0.83 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPRCPTPN11 | |
| SCHEMBL5414176 | 0.82 | PTPN1 (0.56) | PTPN1PTPN2PTPN6PTPRCPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163932-B2 | Aryldifluoromethylphosphonic acids for treatment of diabetes | MERCK FROSST CANADA & CO. (CA) | 2007-01-16 | — | — | US | disclosed |