Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.77 |
| ▸ | MC5R | P33032 | 1/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
| ▸ | MC1R | Q01726 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5411020 | 0.96 | MC4R (0.72) | MC4R | |
| SCHEMBL14593164 | 0.92 | MC4R (0.85) | MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL5406542 | 0.91 | MC4R (0.84) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5405542 | 0.89 | MC4R (0.74) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14592982 | 0.89 | MC4R (0.74) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14593052 | 0.88 | MC4R (0.84) | MC4RMC5RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL5416347 | 0.88 | MC4R (0.83) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14593227 | 0.88 | MC4R (0.79) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14593112 | 0.88 | MC4R (0.79) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14593137 | 0.87 | MC4R (1.00) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |