Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411398 | 1.00 | MC4R (0.59) | MC4RGPR119ALDH1A1KDM4EPOLB | |
| SCHEMBL14593432 | 0.91 | MC4R (0.71) | MC4RGPR119ALDH1A1KDM4ETSHR | |
| SCHEMBL14593390 | 0.88 | MC4R (0.59) | MC4RGPR119ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5413894 | 0.88 | MC4R (0.55) | MC4RGPR119KDM4E | |
| SCHEMBL5418046 | 0.88 | MC4R (0.69) | MC4RGPR119KDM4E | |
| SCHEMBL5417823 | 0.86 | MC4R (0.55) | MC4RGPR119KDM4E | |
| SCHEMBL14593411 | 0.86 | MC4R (0.52) | MC4RGPR119 | |
| SCHEMBL14593357 | 0.86 | MC4R (0.54) | MC4RGPR119KDM4E | |
| SCHEMBL5413683 | 0.86 | MC4R (0.54) | MC4RGPR119KDM4E | |
| SCHEMBL5407759 | 0.83 | MC4R (0.49) | MC4RGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |