SCHEMBL14600342

SCHEMBL14600342

CCCOc1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3cc(-c5c6ccccc6c(-c6ccc(OCCC)cc6)c6ccccc56)ccc3-4)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.44
PDE10A Q9Y233 1/20 0.44
ALK Q9UM73 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
GAA P10253 1/20 0.41
TP53 P04637 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP2C9 P11712 1/20 0.40
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14600417 0.99 PDK2 (0.43) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600408 0.99 PDK2 (0.43) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600484 0.97 PDK2 (0.43) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600324 0.96 PDK2 (0.47) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600390 0.96 PDK2 (0.47) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600430 0.95 PDK2 (0.46) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600379 0.95 PDK2 (0.46) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600453 0.95 PDK2 (0.46) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL10153258 0.95 PDK2 (0.46) PDK2PDE10AALKCYP1A2CYP2C19
SCHEMBL14600493 0.94 PDK2 (0.46) PDK2PDE10AALKCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed