SCHEMBL14600441

SCHEMBL14600441

CCc1nn(-c2ncccc2C)c(Nc2ccc(C)cc2C(=O)O)c1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 14/20 0.56
DHODH Q02127 5/20 0.46
FABP3 P05413 1/20 0.45
FABP4 P15090 1/20 0.45
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4666215 0.93 ADORA1 (0.51) ADORA1DHODHADORA3
SCHEMBL4665259 0.92 ADORA1 (0.51) ADORA1DHODHFABP3FABP4ADORA3
SCHEMBL4668599 0.88 ADORA1 (0.50) ADORA1DHODHADORA3ADORA2AADORA2B
SCHEMBL14600439 0.88 ADORA1 (0.47) ADORA1DHODH
SCHEMBL14600229 0.87 ADORA1 (0.45) ADORA1DHODH
SCHEMBL14600440 0.87 ADORA1 (0.50) ADORA1DHODHADORA3ADORA2AADORA2B
SCHEMBL14600708 0.85 ADORA1 (0.50) ADORA1DHODHADORA3ADORA2AADORA2B
SCHEMBL14600205 0.84 ADORA1 (0.49) ADORA1DHODHFABP3FABP4ADORA3
SCHEMBL14601007 0.83 ADORA1 (0.48) ADORA1DHODHADORA3ADORA2B
SCHEMBL14600266 0.81 ADORA1 (0.54) ADORA1DHODHADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007027842-A1 ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES BAYER HEALTHCARE LLC (US) 2007-03-08 WO disclosed