Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 17/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600230 | 0.91 | ADORA1 (0.47) | ADORA1ADORA2BADORA2AADORA3DHODH | |
| SCHEMBL14600242 | 0.91 | ADORA1 (0.48) | ADORA1ADORA2BADORA2AADORA3TP53 | |
| SCHEMBL4669467 | 0.90 | ADORA1 (0.49) | ADORA1ADORA2BADORA2AADORA3DHODH | |
| SCHEMBL14600241 | 0.90 | ADORA1 (0.46) | ADORA1ADORA2BADORA2AADORA3DHODH | |
| SCHEMBL14600704 | 0.83 | ADORA1 (0.46) | ADORA1ADORA2BADORA2AADORA3DHODH | |
| SCHEMBL14600208 | 0.83 | ADORA1 (0.43) | ADORA1ADORA2BADORA2AADORA3TP53 | |
| SCHEMBL14600656 | 0.82 | ADORA1 (0.43) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL14600233 | 0.82 | ADORA1 (0.46) | ADORA1ADORA2BADORA2AADORA3DHODH | |
| SCHEMBL14600203 | 0.82 | ADORA1 (0.42) | ADORA1ADORA2BADORA2AADORA3DHODH | |
| SCHEMBL14600440 | 0.82 | ADORA1 (0.50) | ADORA1ADORA2BADORA2AADORA3DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |