Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274621 | 0.88 | NR1H4 (0.73) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL273780 | 0.87 | NR1H4 (0.72) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL275327 | 0.86 | NR1H4 (0.63) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL275994 | 0.86 | NR1H4 (0.73) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL273104 | 0.86 | NR1H4 (0.62) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL274682 | 0.85 | NR1H4 (0.80) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL275053 | 0.85 | NR1H4 (0.63) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL275227 | 0.83 | NR1H4 (0.65) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL687653 | 0.82 | NR1H4 (0.56) | NR1H4ABCB1ABCG2CDK4CCND1 | |
| SCHEMBL275399 | 0.82 | NR1H4 (0.75) | NR1H4ABCB1ABCG2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4646293-B2 | — | — | 2011-03-09 | — | — | JP | claimed |
| JP-2005531585-A | — | — | 2005-10-20 | — | — | JP | claimed |
| EP-1532153-A1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X-Ceptor Therapeutics, Inc. (US) | 2005-05-25 | — | — | EP | claimed |
| WO-2003099821-A1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-12-04 | — | — | WO | claimed |