Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801759 | 0.80 | NPC1 (0.44) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL1998938 | 0.79 | PDCD1 (0.47) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL12568272 | 0.79 | CYP11B1 (0.43) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL5991772 | 0.79 | CYP11B1 (0.43) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| Bromide SCHEMBL2002010 | 0.78 | CYP11B1 (0.42) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL26052512 | 0.78 | SMN1; SMN2 (0.48) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL18729757 | 0.76 | CYP11B1 (0.44) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL18814933 | 0.76 | S1PR1 (0.41) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| Bromide SCHEMBL27697063 | 0.75 | CYP11B1 (0.40) | CYP11B1CYP11B2IDO1METAP2PDCD1 | |
| SCHEMBL30873954 | 0.75 | FFAR1 (0.58) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021346-A1 | N-terminally modified GLP-1 receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021346-A1 | N-terminally modified GLP-1 receptor modulators | GLP1R, GIPR, IAPP | CYP11B1 3426/4885CYP11B2 3592/4885IDO1 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.