Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 16/20 | 0.63 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.63 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.63 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24226152 | 0.88 | PTGFR (0.67) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL14627145 | 0.88 | PTGFR (0.67) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL19152027 | 0.84 | PTGFR (0.66) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL23975177 | 0.84 | PTGFR (0.66) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL18939648 | 0.84 | PTGFR (0.66) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL7124357 | 0.82 | PTGFR (0.74) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL7124363 | 0.82 | PTGFR (0.74) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL14624416 | 0.81 | PTGFR (0.62) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL21940493 | 0.81 | PTGFR (0.62) | PTGFRPTGER1PTGER2SLCO2A1KDM4E | |
| SCHEMBL14624750 | 0.81 | PTGFR (0.62) | PTGFRPTGER1PTGER2SLCO2A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161042-B2 | Protected diols for prostaglandin synthesis | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2007-01-09 | — | — | US | disclosed |
| US-7161042-B2 | Protected diols for prostaglandin synthesis | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2007-01-09 | — | — | US | disclosed |