Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.36 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14647 | 0.92 | LPAR1 (0.38) | LPAR1MMELPAR3ABCC3ABCC4 | |
| SCHEMBL1908 | 0.81 | AR (0.38) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL1924 | 0.81 | AR (0.38) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL1728 | 0.81 | LPAR1 (0.52) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL2059 | 0.81 | LPAR1 (0.52) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL17265466 | 0.79 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL18597871 | 0.79 | BRD4 (0.36) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL6902 | 0.79 | FFAR1 (0.41) | LPAR1FFAR1 | |
| SCHEMBL7497 | 0.79 | FFAR1 (0.41) | LPAR1FFAR1 | |
| SCHEMBL7100 | 0.79 | FFAR1 (0.41) | LPAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |