SCHEMBL14604113

SCHEMBL14604113

CCCN(CCC)C[C@@H]1CCCN1C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc(-c3ccc(Cl)s3)s2)C1=O

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14604268 0.94 F10 (0.71) F10
SCHEMBL14604341 0.91 F10 (0.73) F10
SCHEMBL14604467 0.89 F10 (0.71) F10
SCHEMBL14604193 0.89 F10 (0.68) F10
SCHEMBL14604463 0.88 F10 (0.69) F10
SCHEMBL14604196 0.88 F10 (0.69) F10
SCHEMBL5649225 0.87 F10 (0.77) F10
SCHEMBL14604264 0.87 F10 (0.70) F10
SCHEMBL14604186 0.87 F10 (0.70) F10
SCHEMBL14604059 0.87 F10 (0.72) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166586-B2 Sulfonamide lactam inhibitors of FXa and method BRISTOL MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
US-7166586-B2 Sulfonamide lactam inhibitors of FXa and method BRISTOL MYERS SQUIBB CO. (US) 2007-01-23 US disclosed