Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14604229 | 0.94 | MAPK8 (0.49) | MAPK8GRIN1 | |
| SCHEMBL14604008 | 0.94 | MAPK8 (0.48) | MAPK8GRIN1 | |
| SCHEMBL14604103 | 0.93 | MAPK8 (0.51) | MAPK8GRIN1 | |
| SCHEMBL14604210 | 0.92 | MAPK8 (0.51) | MAPK8GRIN1 | |
| SCHEMBL14604194 | 0.91 | MAPK8 (0.51) | MAPK8 | |
| SCHEMBL14604343 | 0.91 | MAPK8 (0.55) | MAPK8 | |
| SCHEMBL14604063 | 0.91 | MAPK8 (0.56) | MAPK8 | |
| SCHEMBL14604335 | 0.91 | MAPK8 (0.54) | MAPK8GRIN1 | |
| SCHEMBL14604228 | 0.90 | MAPK8 (0.54) | MAPK8 | |
| SCHEMBL14604039 | 0.89 | MAPK8 (0.51) | MAPK8GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2731932-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-05-21 | — | — | EP | claimed |
| WO-2013007676-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | claimed |