SCHEMBL14604244

CCOC(=O)CNC(=O)N(C)C1CCN(C[C@@H]2CCCN2C(=O)CN2CCC[C@H](NS(=O)(=O)/C=C/c3ccc(Cl)s3)C2=O)C1

nearest known ligand 0.55

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	20/20	0.55

▸	F2	P00734	1/20	0.39

▸	KLKB1	P03952	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14604643	0.92	F10 (0.59)	F10F2KLKB1
SCHEMBL14604640	0.91	F10 (0.58)	F10F2KLKB1
SCHEMBL14604811	0.91	F10 (0.61)	F10F2KLKB1
SCHEMBL14604542	0.89	F10 (0.61)	F10F2KLKB1
SCHEMBL14604301	0.89	F10 (0.59)	F10F2KLKB1
SCHEMBL14604806	0.89	F10 (0.59)	F10F2KLKB1
SCHEMBL14604817	0.89	F10 (0.60)	F10F2KLKB1
SCHEMBL5644288	0.89	F10 (0.62)	F10F2KLKB1
SCHEMBL5644292	0.89	F10 (0.62)	F10F2KLKB1
SCHEMBL14604809	0.89	F10 (0.62)	F10F2KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7166586-B2	Sulfonamide lactam inhibitors of FXa and method	BRISTOL MYERS SQUIBB CO. (US)	2007-01-23	—	—	US	disclosed
US-7166586-B2	Sulfonamide lactam inhibitors of FXa and method	BRISTOL MYERS SQUIBB CO. (US)	2007-01-23	—	—	US	disclosed