Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14575716 | 0.92 | MAPK8 (1.00) | MAPK8 | |
| SCHEMBL17366078 | 0.91 | MAPK8 (0.87) | MAPK8 | |
| SCHEMBL14576885 | 0.91 | MAPK8 (1.00) | MAPK8 | |
| SCHEMBL14605130 | 0.89 | MAPK8 (0.82) | MAPK8 | |
| SCHEMBL17360900 | 0.88 | MAPK8 (0.81) | MAPK8 | |
| SCHEMBL15703710 | 0.86 | MAPK8 (0.84) | MAPK8 | |
| SCHEMBL14605201 | 0.86 | MAPK8 (0.83) | MAPK8 | |
| SCHEMBL17360932 | 0.85 | MAPK8 (0.78) | MAPK8 | |
| SCHEMBL17360980 | 0.84 | MAPK8 (0.86) | MAPK8 | |
| SCHEMBL17360917 | 0.84 | MAPK8 (0.77) | MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2731932-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-05-21 | — | — | EP | claimed |
| WO-2013007676-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-01-17 | — | — | WO | claimed |