SCHEMBL14604358

SCHEMBL14604358

NC(Cc1c[nH]cn1)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.35
▸ MME P08473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14604365 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL29891666 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL30822978 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL30629016 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL10856404 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL29630376 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL30159237 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL29519255 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL30712894 1.00 SLC15A2 (0.35) SLC15A2MME
SCHEMBL23598223 0.97 MME (0.35) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322900-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME BIOVERATIV THERAPEUTICS INC (US) 2023-10-12 — — US disclosed
EP-4194465-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME Bioverativ Therapeutics Inc. (US) 2023-06-14 — — EP disclosed
CN-114699506-A Use of recombinant calreticulin for growing hair, protecting hair or preventing alopecia and related products 北京百华百汇生物科技有限公司 2022-07-05 — — CN disclosed
US-20200087379-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME BIOVERATIV THERAPEUTICS INC (US) 2020-03-19 — — US disclosed
EP-2814840-B1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME BIOVERATIV THERAPEUTICS INC (US) 2019-11-13 — — EP disclosed
EP-3564260-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME Bioverativ Therapeutics Inc. (US) 2019-11-06 — — EP disclosed
US-10421798-B2 Factor VIII compositions and methods of making and using same BIOVERATIV THERAPEUTICS INC. (US) 2019-09-24 — — US disclosed
EP-3339325-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB Biopharma SPRL (BE) 2018-06-27 — — EP disclosed
US-9957328-B2 Bacterial host strain expressing recombinant DSBC UCB PHARMA, S.A. (GB) 2018-05-01 — — US disclosed
US-20170335003-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC CELLTECH R&D LTD. (GB) 2017-11-23 — — US disclosed
EP-2731973-B1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB BIOPHARMA SPRL (BE) 2017-11-15 — — EP disclosed
US-9725516-B2 Bacterial host strain expressing recombinant DSBC UCB PHARMA, S.A. (BE) 2017-08-08 — — US disclosed
US-20150158929-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME AMUNIX OPERATING INC. (US) 2015-06-11 — — US disclosed
CN-104487452-A Factor viii compositions and methods of making and using same AMUNIX OPERATING INC 2015-04-01 — — CN disclosed
EP-2814840-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME Amunix Operating Inc. (US) 2014-12-24 — — EP disclosed
US-20140141468-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB PHARMA, S.A. (BE) 2014-05-22 — — US disclosed
EP-2731973-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB Pharma, S.A. (BE) 2014-05-21 — — EP disclosed
WO-2013122617-A1 FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME AMUNIX OPERATING INC. (US) 2013-08-22 — — WO disclosed
WO-2013007388-A1 BACTERIAL HOST STRAIN EXPRESSING RECOMBINANT DSBC UCB PHARMA, S.A. (BE) 2013-01-17 — — WO disclosed
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