SCHEMBL14604591

SCHEMBL14604591

NC(=O)[C@@H]1CCCN1C[C@@H]1CCCN1C(=O)CN1CCC[C@H](NS(=O)(=O)c2ccc(-c3ccc(Cl)s3)s2)C1=O

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14604403 0.92 F10 (0.66) F10
SCHEMBL14604472 0.92 F10 (0.66) F10
SCHEMBL14604376 0.91 F10 (0.65) F10
SCHEMBL14604478 0.91 F10 (0.66) F10
SCHEMBL14604605 0.90 F10 (0.70) F10
SCHEMBL14604356 0.89 F10 (0.68) F10
SCHEMBL14603310 0.88 F10 (0.77) F10
SCHEMBL14604788 0.88 F10 (0.76) F10
SCHEMBL14604545 0.88 F10 (0.76) F10
SCHEMBL14604785 0.88 F10 (0.76) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166586-B2 Sulfonamide lactam inhibitors of FXa and method BRISTOL MYERS SQUIBB CO. (US) 2007-01-23 US disclosed
US-7166586-B2 Sulfonamide lactam inhibitors of FXa and method BRISTOL MYERS SQUIBB CO. (US) 2007-01-23 US disclosed