Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14603303 | 0.93 | F10 (0.70) | F10F2KLKB1 | |
| SCHEMBL14604550 | 0.92 | F10 (0.69) | F10F2KLKB1 | |
| SCHEMBL14604800 | 0.91 | F10 (0.68) | F10F2KLKB1 | |
| SCHEMBL14604798 | 0.91 | F10 (0.70) | F10F2KLKB1 | |
| SCHEMBL14604252 | 0.91 | F10 (0.70) | F10F2KLKB1 | |
| SCHEMBL14603572 | 0.91 | F10 (0.69) | F10F2KLKB1 | |
| SCHEMBL14603255 | 0.91 | F10 (0.76) | F10F2KLKB1 | |
| SCHEMBL14604471 | 0.91 | F10 (0.67) | F10F2KLKB1 | |
| SCHEMBL14604797 | 0.91 | F10 (0.67) | F10F2KLKB1 | |
| SCHEMBL14603300 | 0.90 | F10 (0.75) | F10F2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166586-B2 | Sulfonamide lactam inhibitors of FXa and method | BRISTOL MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |