Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.91 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631566 | 0.85 | SYK (0.81) | SYK | |
| SCHEMBL28757116 | 0.84 | SYK (0.80) | SYK | |
| SCHEMBL657059 | 0.84 | SYK (0.77) | SYK | |
| SCHEMBL655134 | 0.84 | SYK (0.77) | SYK | |
| SCHEMBL8999981 | 0.83 | SYK (1.00) | SYK | |
| SCHEMBL27631853 | 0.83 | SYK (0.82) | SYK | |
| SCHEMBL27631777 | 0.83 | SYK (0.82) | SYK | |
| SCHEMBL30010055 | 0.82 | SYK (1.00) | SYK | |
| SCHEMBL27631831 | 0.81 | SYK (0.81) | SYK | |
| SCHEMBL27612555 | 0.81 | SYK (0.83) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027238-A2 | JAK KINASE INHIBITORS AND THEIR USES | RIGEL PHARMACEUTICALS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |