Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.43 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601795 | 0.89 | MCL1 (0.56) | MCL1LMNAMEN1KMT2APTPN11 | |
| SCHEMBL14610854 | 0.87 | MCL1 (0.52) | MCL1HTR2BLMNAMAPTMEN1 | |
| SCHEMBL14610856 | 0.87 | MCL1 (0.55) | MCL1HTR2BLMNAMAPTMEN1 | |
| SCHEMBL14610852 | 0.86 | PTPN11 (0.49) | HTR2BLMNAMAPTMEN1NR1I2 | |
| SCHEMBL7959110 | 0.86 | MAPT (0.54) | HTR2BLMNAMAPTMEN1NR1I2 | |
| SCHEMBL14610787 | 0.85 | PTPN11 (0.45) | MCL1HTR2BLMNAMAPTMEN1 | |
| SCHEMBL14610802 | 0.82 | PTPN11 (0.50) | HTR2BLMNAMAPTMEN1NR1I2 | |
| SCHEMBL14610803 | 0.82 | PTPN11 (0.43) | MCL1HTR2BLMNAMAPTMEN1 | |
| SCHEMBL14610489 | 0.82 | PTPN11 (0.45) | HTR2BLMNAMAPTMEN1NR1I2 | |
| SCHEMBL14610850 | 0.82 | LCLAT1 (0.43) | MCL1HTR2BLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |