SCHEMBL14611380

SCHEMBL14611380

CCCCC[C@H](CNO)C(=O)N1CCC[C@H]1C(=O)NC(=O)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.37
POLB P06746 1/20 0.35
REN P00797 2/20 0.35
ACE P12821 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600121 0.83
SCHEMBL4600126 0.83
SCHEMBL2208193 0.83
SCHEMBL2211369 0.70 F2 (0.38)
SCHEMBL15196130 0.70 F2 (0.38)
SCHEMBL2210117 0.70 NPSR1 (0.36) NPSR1
SCHEMBL20811479 0.70 DPP4 (0.45) RENACE
SCHEMBL21887101 0.70 ACE (0.56) RENACE
SCHEMBL2207874 0.69 NPSR1 (0.36) NPSR1RENACE
SCHEMBL14465011 0.69 PEPD (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007016364-A2 PEPTIDE DEFORMYLASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2007-02-08 WO disclosed