⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12259753 | 1.00 | — | — | |
| SCHEMBL11206393 | 1.00 | — | — | |
| SCHEMBL10288542 | 0.83 | — | — | |
| SCHEMBL8246948 | 0.83 | — | — | |
| SCHEMBL10070125 | 0.82 | DPP7 (0.53) | — | |
| SCHEMBL15308952 | 0.81 | — | — | |
| SCHEMBL13973032 | 0.81 | — | — | |
| SCHEMBL18612630 | 0.79 | DPP7 (0.55) | — | |
| SCHEMBL21728716 | 0.79 | DPP7 (0.41) | — | |
| SCHEMBL31615214 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013790-A1 | ANTIMICROBIAL COMPOUNDS AND USES THEREOF | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |
| US-7183307-B2 | Pyrazole-derived kinase inhibitors and uses thereof | VERTEX PHARMACEUTICALS INCROPORATED (US) | 2007-02-27 | — | — | US | disclosed |