Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 14/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 4/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748676 | 0.85 | DPP4 (0.49) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748677 | 0.85 | DPP4 (0.49) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748433 | 0.85 | DPP4 (0.49) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748434 | 0.85 | DPP4 (0.49) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748767 | 0.82 | DPP4 (0.47) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748770 | 0.82 | DPP4 (0.47) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748779 | 0.82 | DPP4 (0.48) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL4778870 | 0.82 | DPP4 (0.48) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL4778879 | 0.82 | DPP4 (0.48) | HDAC8DPP4HDAC1HDAC3HDAC2 | |
| SCHEMBL1748778 | 0.82 | DPP4 (0.48) | HDAC8DPP4HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021990-A2 | MELANOCORTIN RECEPTOR-SPECIFIC PIPERAZINE COMPOUNDS WITH DIAMINE GROUPS | PALATIN TECHNOLOGIES, INC. (US) | 2007-02-22 | — | — | WO | disclosed |