Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.75 |
| ▸ | HPGD | P15428 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416357 | 0.92 | KDM4E (0.80) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL14010118 | 0.91 | KDM4E (0.68) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL5003817 | 0.91 | KDM4E (0.68) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL16024499 | 0.89 | KDM4E (0.78) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL5006539 | 0.89 | KDM4E (0.85) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL16011450 | 0.89 | KDM4E (0.85) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL5009602 | 0.88 | KDM4E (0.76) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL1706103 | 0.88 | KDM4E (0.76) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL16011449 | 0.87 | KDM4E (0.82) | KDM4EHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL5006518 | 0.86 | KDM4E (0.76) | KDM4EHPGDALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017762-A2 | PHOSPHONATED FLUOROQUINOLONES, ANTIBACTERIAL ANALOGS THEREOF, AND METHODS FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-02-15 | — | — | WO | disclosed |