⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640689 | 0.71 | — | — | |
| SCHEMBL12510810 | 0.71 | — | — | |
| SCHEMBL1647187 | 0.70 | — | — | |
| SCHEMBL21376 | 0.69 | — | — | |
| SCHEMBL31576596 | 0.69 | — | — | |
| SCHEMBL52388 | 0.69 | — | — | |
| SCHEMBL21376217 | 0.67 | — | — | |
| SCHEMBL10772647 | 0.66 | TSHR (0.69) | — | |
| SCHEMBL18187333 | 0.66 | TSHR (0.69) | — | |
| Charcoal, Activated SCHEMBL10803707 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037206-A1 | Polypeptide of given sequence and antibodies that bind; gene expression; treatment of muscular dystrophy and cystic fibrosis | HUMAN GENOME SCIENCES, INC. | 2007-02-15 | — | — | US | disclosed |