SCHEMBL14616810

SCHEMBL14616810

COCCn1c(-c2cnc(-c3ccc4scnc4c3)[nH]2)nc2c(N3C[C@@H](CO)OC[C@@H]3C)nccc21

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RIPK2 O43353 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14616817 0.92 RIPK2 (0.37) RIPK2
SCHEMBL14576181 0.89 TTK (0.30) —
SCHEMBL14616808 0.88 RIPK2 (0.37) RIPK2
SCHEMBL14616809 0.88 RIPK2 (0.37) RIPK2
SCHEMBL14616826 0.85 RIPK2 (0.38) RIPK2
SCHEMBL14616811 0.84 TTK (0.38) RIPK2
SCHEMBL14616812 0.83 RIPK2 (0.41) RIPK2
SCHEMBL14616813 0.83 RIPK2 (0.41) RIPK2
SCHEMBL14616816 0.83 RIPK2 (0.36) RIPK2
SCHEMBL14616807 0.83 RIPK2 (0.40) RIPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130018039-A1 IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2013-01-17 — — US disclosed
US-20130018039-A1 IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2013-01-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130018039-A1 IMIDAZOLYL-IMIDAZOLES AS KINASE INHIBITORS MAP3K19, MAP3K20, MAP3K3 RIPK2 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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