Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410368 | 1.00 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616848 | 1.00 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL209403 | 0.97 | HSD17B10 (0.50) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616846 | 0.93 | HSD17B10 (0.43) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616845 | 0.93 | HSD17B10 (0.43) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL16473876 | 0.90 | HSD17B10 (0.44) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| Ether SCHEMBL11844631 | 0.90 | HSD17B10 (0.44) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14616851 | 0.89 | HSD17B10 (0.40) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL23408864 | 0.87 | HSD17B10 (0.46) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14870365 | 0.87 | LPAR1 (0.38) | HSD17B10TDP1LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018010-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | ENZON PHARMACEUTICALS, INC. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018010-A1 | POLYMERIC CONJUGATES OF ADENINE NUCLEOSIDE ANALOGS | VEGFA, MKI67, PCNA | HSD17B10 4271/4885TDP1 1879/4885LPAR1 2024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.