Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 9/20 | 0.54 |
| ▸ | CDK9 | P50750 | 12/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1946243 | 1.00 | CCNT1 (0.54) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1945774 | 0.92 | CCNT1 (0.56) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1462654 | 0.92 | CCNT1 (0.56) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1463048 | 0.92 | CCNT1 (0.56) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1464297 | 0.91 | CCNT1 (0.47) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1462530 | 0.91 | CCNT1 (0.47) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1948331 | 0.91 | CCNT1 (0.47) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1945132 | 0.91 | CCNT1 (0.47) | CCNT1CDK9SMN1; SMN2 | |
| SCHEMBL1439529 | 0.89 | CCNT1 (0.60) | CCNT1CDK9 | |
| SCHEMBL1439813 | 0.89 | CCNT1 (0.60) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | claimed |
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |