Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148571 | 0.90 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1 | |
| SCHEMBL1147829 | 0.79 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1 | |
| SCHEMBL1147983 | 0.77 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148791 | 0.76 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1FYN | |
| SCHEMBL14525254 | 0.76 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148633 | 0.75 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1 | |
| SCHEMBL14618214 | 0.73 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1 | |
| SCHEMBL3106385 | 0.73 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148599 | 0.72 | FGFR1 (0.39) | HSP90AA1HSP90AB1 | |
| SCHEMBL1147959 | 0.71 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021877-A1 | IMIDAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-02-22 | — | — | WO | disclosed |