Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990376 | 0.84 | CYP3A4 (0.51) | SMN1; SMN2HPGDUSP2CNR1CYP2C19 | |
| SCHEMBL3988996 | 0.82 | CYP3A4 (0.50) | HPGDUSP2CNR1CYP2C19CYP3A4 | |
| SCHEMBL3988800 | 0.78 | KMT2A (0.44) | ALDH1A1SMN1; SMN2HPGDUSP2GAA | |
| SCHEMBL3987827 | 0.73 | CNR1 (0.64) | ALDH1A1SMN1; SMN2HPGDCNR1CYP2C19 | |
| SCHEMBL12697375 | 0.72 | TSHR (0.51) | ALDH1A1SMN1; SMN2HPGDUSP2CNR1 | |
| SCHEMBL3989645 | 0.72 | CNR2 (0.48) | CNR1CYP2C19CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3989648 | 0.72 | CNR1 (0.48) | ALDH1A1HPGDUSP2CNR1CYP2C19 | |
| SCHEMBL3992803 | 0.70 | CNR2 (0.79) | ALDH1A1SMN1; SMN2HPGDCNR1CYP2C19 | |
| SCHEMBL12697435 | 0.70 | CNR2 (0.48) | ALDH1A1HPGDCNR1CNR2LMNA | |
| Hydrochloric Acid SCHEMBL3993464 | 0.70 | CNR2 (0.78) | ALDH1A1SMN1; SMN2HPGDCNR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017264-A2 | PYRROLOPYRIDINEDERIVATIVES AS MODULATORS OF THE CANNABINOID RECEPTOR FOR THE TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | GLAXO GROUP LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |