⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylmalonic Acid SCHEMBL29116658 | 0.83 | TP53 (0.47) | — | |
| SCHEMBL334917 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL27994947 | 0.79 | TP53 (0.33) | — | |
| Methylmalonic Acid SCHEMBL27766 | 0.78 | — | — | |
| Methylmalonic Acid SCHEMBL27881917 | 0.78 | TP53 (0.57) | — | |
| SCHEMBL27511564 | 0.75 | — | — | |
| Methylmalonic Acid SCHEMBL11586861 | 0.74 | — | — | |
| Methylmalonic Acid SCHEMBL2572891 | 0.74 | — | — | |
| Methylmalonic Acid SCHEMBL105829 | 0.74 | — | — | |
| Methylmalonic Acid SCHEMBL5874913 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63012341-A | — | — | None | — | — | JP | disclosed |
| CN-119072546-A | Transgenic soybean strain GM_CSM63714, detection method and application thereof | 孟山都技术公司 | 2024-12-03 | — | — | CN | disclosed |
| US-10717738-B2 | Pyrimidinone and its derivatives inhibiting factor XIa | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-07-21 | — | — | US | disclosed |
| EP-3290413-B9 | PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS | ONO PHARMACEUTICAL CO (JP) | 2020-04-29 | — | — | EP | disclosed |
| EP-3290413-B1 | PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS | ONO PHARMACEUTICAL CO (JP) | 2019-11-13 | — | — | EP | disclosed |
| EP-3290413-A1 | PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS | ONO Pharmaceutical Co., Ltd. (JP) | 2018-03-07 | — | — | EP | disclosed |
| EP-2794597-B1 | PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS | ONO PHARMACEUTICAL CO (JP) | 2017-11-15 | — | — | EP | disclosed |
| US-20170305917-A1 | COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-10-26 | — | — | US | disclosed |
| US-9732085-B2 | Pyridinone and pyrimidinone derivatives as factor Xia | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-08-15 | — | — | US | disclosed |
| US-9102592-B2 | Intermediate compounds and processes for the preparation of quinoline derivatives such as laquinimod sodium | MAPI PHARMA LTD. (IL) | 2015-08-11 | — | — | US | disclosed |
| WO-1995004057-A1 | TRICYCLIC INHIBITORS OF THE GPIIbIIIa RECEPTOR | GENENTECH, INC. (US) | 1995-02-09 | — | — | WO | disclosed |
| US-5232462-A | Lightfast, colorfast | CIBA-GEIGY CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-5177071-A | 1,4-BENZODIAZEPINES WITH 6-MEMBERED HETEROCYCLIC RINGS TO TREAT PANIC AND ANXIETY DISORDER | MERCK & CO., INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0519678-A2 | 1,4-Benzodiazepines with 6-membered heterocyclic rings | MERCK & CO. INC. (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4816499-A | Porous inorganic particles modified with amino and carboxyl groups | DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1989-03-28 | — | — | US | disclosed |
| EP-0272868-A1 | 1,4-Benzodiazepines with 6-membered heterocyclic rings | MERCK & CO. INC. (US) | 1988-06-29 | — | — | EP | disclosed |
| JP-S6312341-A | METHOD FOR REFORMING POROUS SUBSTANCE | AGENCY OF IND SCIENCE & TECHNOL | 1988-01-19 | — | — | JP | disclosed |
| US-4336380-A | FOR USE AS HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-4329473-A | HYPOTENSIVE AGENTS | SRI INTERNATIONAL | 1982-05-11 | — | — | US | disclosed |
| US-4276417-A | TREATMENT OF VASCULAR-CONDITION HYPERTENSION | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |