Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312015 | 0.77 | HTT (0.57) | MAPTHTTTSHRHSD17B10L3MBTL1 | |
| SCHEMBL1462240 | 0.76 | MAPT (0.58) | MAPTHTTTSHRHSD17B10L3MBTL1 | |
| Nitrobenzene SCHEMBL28244051 | 0.76 | MAPT (0.51) | MAPTHTTTSHRHSD17B10L3MBTL1 | |
| SCHEMBL20503479 | 0.76 | GAA (0.48) | MAPTALDH1A1KDM4ECYP1A2GAA | |
| SCHEMBL15352874 | 0.74 | HTT (0.66) | MAPTHTTALDH1A1KDM4EGAA | |
| SCHEMBL19456984 | 0.74 | HTT (1.00) | MAPTHTTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL27315259 | 0.74 | HTT (0.60) | MAPTHTTALDH1A1KDM4EKMT2A | |
| SCHEMBL19456939 | 0.73 | HTT (0.64) | MAPTHTTALDH1A1KDM4EKMT2A | |
| SCHEMBL27312016 | 0.72 | HTT (0.59) | MAPTHTTTSHRALDH1A1KDM4E | |
| SCHEMBL9369399 | 0.72 | HTT (0.68) | MAPTHTTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933246-B2 | Process for preparing 1-phenylpyrazoles | BASF SE (DE) | 2015-01-13 | — | — | US | disclosed |
| EP-2473485-B1 | PROCESS FOR PREPARING 1-PHENYLPYRAZOLES | BASF SE (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-20130131352-A1 | Process for Preparing 1-phenylpyrazoles | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| US-8362271-B2 | Process for preparing 1-phenylpyrazoles | BASF SE (DE) | 2013-01-29 | — | — | US | disclosed |
| EP-2473485-A1 | PROCESS FOR PREPARING 1-PHENYLPYRAZOLES | BASF SE (DE) | 2012-07-11 | — | — | EP | disclosed |
| US-20120165544-A1 | Process for Preparing 1-Phenylpyrazoles | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| WO-2011026937-A1 | PROCESS FOR PREPARING 1-PHENYLPYRAZOLES | BASF SE (DE) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131352-A1 | Process for Preparing 1-phenylpyrazoles | CBR1, CBR3, CYP1A1 | MAPT 4574/4885HTT 2226/4885TSHR 148/4885 |
| US-20120165544-A1 | Process for Preparing 1-Phenylpyrazoles | AP3B1, AP3M1, AP3D1 | MAPT 4636/4885HTT 2827/4885TSHR 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.