Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624360 | 0.89 | HDAC1 (0.59) | SMN1; SMN2HDAC1HDAC8HDAC6FFAR1 | |
| SCHEMBL14624440 | 0.84 | NOTUM (0.54) | HDAC1HDAC6ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13228095 | 0.83 | HDAC1 (0.54) | APPGAASMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL13209391 | 0.81 | HDAC1 (0.48) | APPGAASMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL14624335 | 0.81 | NPY5R (0.47) | — | |
| SCHEMBL14530335 | 0.77 | HDAC1 (0.59) | APPGAASMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL13209332 | 0.77 | NOTUM (0.51) | FFAR1 | |
| SCHEMBL13518854 | 0.76 | AKT1 (0.47) | HDAC1HDAC8HDAC6FFAR1 | |
| SCHEMBL12315950 | 0.76 | CHRM4 (0.47) | APPGAASMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL13518853 | 0.75 | NOTUM (0.41) | HDAC1HDAC8HDAC6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002637-A1 | N-LINKED HETEROCYCLIC ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |