Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879156 | 0.93 | PTGDR2 (0.47) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL3145833 | 0.93 | PTGDR2 (0.47) | PTGDR2MTNR1AMTNR1BADAM17HDAC1 | |
| SCHEMBL1875711 | 0.92 | PTGDR2 (0.46) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL12637103 | 0.91 | PTGDR2 (0.45) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL1878855 | 0.91 | PTGDR2 (0.45) | PTGDR2MTNR1AMTNR1BTBXA2RADAM17 | |
| SCHEMBL1885428 | 0.91 | PTGDR2 (0.45) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL1871468 | 0.89 | PTGDR2 (0.49) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL12637031 | 0.88 | PTGDR2 (0.48) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL1877449 | 0.88 | PTGDR2 (0.50) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL1877855 | 0.88 | PTGDR2 (0.48) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |