Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624296 | 0.85 | HTR1B (0.56) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL14624578 | 0.85 | HTR1B (0.56) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL14624591 | 0.85 | HTR1B (0.56) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL1880414 | 0.84 | HTR1B (0.50) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL1874230 | 0.84 | HTR1B (0.50) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL14624292 | 0.82 | HTR1B (0.53) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL19847265 | 0.80 | HTR1B (0.68) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL12637222 | 0.79 | HTR1B (0.48) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL1873522 | 0.79 | HTR1B (0.48) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL14623662 | 0.78 | CA1 (0.48) | HTR1BHTR1AHTR1DDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |