Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19966100 | 0.86 | CARM1 (0.41) | PAOXSIGMAR1ACE2ALDH1A1 | |
| SCHEMBL21386205 | 0.81 | HRH3 (0.52) | SMN1; SMN2 | |
| SCHEMBL4392341 | 0.81 | ACE2 (0.50) | PAOXSIGMAR1TP53SMN1; SMN2KMT2A | |
| SCHEMBL14824991 | 0.79 | HRH3 (0.56) | SMN1; SMN2 | |
| SCHEMBL1269079 | 0.79 | CARM1 (0.50) | PAOXSIGMAR1TP53SMN1; SMN2KMT2A | |
| SCHEMBL6429155 | 0.77 | PAOX (0.42) | PAOXSIGMAR1TP53SMN1; SMN2KMT2A | |
| SCHEMBL4760025 | 0.77 | PAOX (0.42) | PAOXSIGMAR1TP53SMN1; SMN2KMT2A | |
| SCHEMBL6663287 | 0.77 | PAOX (0.60) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6657767 | 0.77 | PAOX (0.54) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20234244 | 0.77 | PAOX (0.60) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | disclosed |