⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567298 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL8956839 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL1462499 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL9400784 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL988701 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL23929272 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL3366462 | 0.97 | EPHX1 (0.58) | — | |
| SCHEMBL10809979 | 0.97 | EPHX1 (0.58) | — | |
| Hydrochloric Acid SCHEMBL8615469 | 0.95 | EPHX1 (0.56) | — | |
| Hydrochloric Acid SCHEMBL875477 | 0.95 | EPHX1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114998-A1 | NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS | Centre National de la Recherche Scientifique (FR) | 2009-11-11 | — | — | EP | claimed |
| WO-2008110695-A1 | NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-09-18 | — | — | WO | claimed |
| US-5116817-A | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1992-05-26 | — | — | US | claimed |
| EP-0097031-B1 | NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1988-09-21 | — | — | EP | claimed |
| EP-0111841-B1 | LHRH PREPARATIONS FOR INTRANASAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1987-05-06 | — | — | EP | claimed |
| US-4476116-A | HORMONES; PROTEINS; ENZYMERS | SYNTEX (U.S.A.) INC. (US) | 1984-10-09 | — | — | US | claimed |
| EP-0111841-A1 | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1984-06-27 | — | — | EP | claimed |
| EP-0097031-A2 | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-12-28 | — | — | EP | claimed |
| US-20240216389-A1 | DRUG FOR PREVENTING AND/OR TREATING POLYCYSTIC KIDNEY DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-07-04 | — | — | US | disclosed |
| US-11957691-B2 | Drug for preventing and/or treating polycystic kidney disease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-04-16 | — | — | US | disclosed |
| US-11147821-B2 | Drug for preventing and/or treating polycystic kidney disease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11013746-B2 | Drug for preventing and/or treating polycystic kidney disease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-05-25 | — | — | US | disclosed |
| US-20190117666-A1 | DRUG FOR PREVENTING AND/OR TREATING POLYCYSTIC KIDNEY DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
| US-10081717-B2 | Polymeric materials | COLORMATRIX HOLDINGS, INC. (US) | 2018-09-25 | — | — | US | disclosed |
| US-4036848-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-4033753-A | HERICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4023957-A | Herbicidal 1-thiadiazolyl-5-carbamoyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4018787-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |
| US-4008068-A | HERBICIDE | VELSICOL CHEMICAL CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-3950323-A | Digoxigenine-3-[2',3'-didesoxy-glycosides] and a process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |