SCHEMBL146249

SCHEMBL146249

C=C/C=[C]\C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL834721 1.00
SCHEMBL120438 1.00
SCHEMBL4663521 0.77
SCHEMBL10400212 0.74
SCHEMBL21596733 0.74
SCHEMBL10400213 0.74
SCHEMBL6183389 0.71
SCHEMBL2400269 0.71
SCHEMBL2400267 0.71
SCHEMBL8901028 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139282-A1 ANTIMALARIAL AGENTS MERCK SHARP & DOHME LLC (US) 2023-05-04 US disclosed
EP-4100401-A1 ANTIMALARIAL AGENTS Merck Sharp & Dohme LLC (US) 2022-12-14 EP disclosed
CN-107574178-B Fungal artificial chromosomes, compositions, methods and uses 完整基因技术公司 2022-05-27 CN disclosed
WO-2021155791-A1 ANTIMALARIAL AGENTS MERCK SHARP & DOHME CORP. (US) 2021-08-12 WO disclosed
WO-2021155612-A1 ANTIMALARIAL AGENTS MERCK SHARP & DOHME CORP. (US) 2021-08-12 WO disclosed
WO-2021105075-A1 DIBENZOPYRAN AMPK ACTIVATOR COMPOUNDS, COMPOSITIONS, METHODS AND USES THEREOF Société des Produits Nestlé S.A. (CH) 2021-06-03 WO disclosed
EP-3810720-A1 EXTRUDED PET FILMS WITH PHOTOSTABLE DYES FOR COLOR CONVERSION BASF SE (DE) 2021-04-28 EP disclosed
CN-106573235-B Iron hydrosilylate catalyst 国立大学法人九州大学 2020-07-07 CN disclosed
WO-2019243288-A1 EXTRUDED PET FILMS WITH PHOTOSTABLE DYES FOR COLOR CONVERSION BASF SE (DE) 2019-12-26 WO disclosed
EP-3558303-A1 AMINO ACID COMPOUNDS AND METHODS OF USE Pliant Therapeutics, Inc. (US) 2019-10-30 EP disclosed
EP-0938842-A1 Sustained release pheromone dispenser SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-09-01 EP disclosed
EP-0877730-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1998-11-18 EP disclosed
US-5739140-A AGRICULTURAL FUNGICIDES MONSANTO COMPANY (US) 1998-04-14 US disclosed
WO-1997016413-A9 ARYL ACRYLICS FOR USE AS FUNGICIDE 1997-08-14 WO disclosed
WO-1997016413-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1997-05-09 WO disclosed
US-5250426-A Catalytic hydrolysis using monoclonal antibodies THE SCRIPPS RESEARCH INSTITUTE (US) 1993-10-05 US disclosed
EP-0421302-A2 Process for producing enyne derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-04-10 EP disclosed
US-4349552-A TREATMENT OF CANCER FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1982-09-14 US disclosed
EP-0010941-A1 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-05-14 EP disclosed
US-3989739-A PERFUMES FIRMENICH S.A. (CH) 1976-11-02 US disclosed