⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349777 | 0.71 | — | — | |
| SCHEMBL13955492 | 0.67 | — | — | |
| SCHEMBL7204972 | 0.67 | — | — | |
| SCHEMBL13347918 | 0.65 | — | — | |
| SCHEMBL9059350 | 0.65 | — | — | |
| SCHEMBL9059976 | 0.65 | — | — | |
| SCHEMBL20865551 | 0.65 | — | — | |
| SCHEMBL15996708 | 0.65 | — | — | |
| SCHEMBL18874730 | 0.63 | — | — | |
| SCHEMBL15100908 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2985021-A1 | USE OF AMIDOXIME CARBOXYLIC ACID ESTERS AND N-HYDROXYGUANIDINE CARBOXYLIC ACID ESTERS FOR PRODUCING PRODRUGS | Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-9040516-B2 | Uracil derivative and use thereof for medical purposes | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-20140179670-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| WO-2007005366-A1 | AMlNO-5-(5-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR β-SECRETASE MODULATION | WYETH (US) | 2007-01-11 | — | — | WO | disclosed |