SCHEMBL1462648

SCHEMBL1462648

CCC(CC)(C(=O)O)C(CC)(C(=O)O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
FFAR3 O14843 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 2/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147483 0.82 FFAR3 (0.41) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL232174 0.75
SCHEMBL3053815 0.74 TSHR (0.40) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL471905 0.74 FFAR3 (0.35) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL276477 0.74 TSHR (0.40) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL5850679 0.74 FFAR3 (0.35) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL21269356 0.72 TSHR (0.38) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL5003423 0.72 TSHR (0.38) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL21269186 0.72 TSHR (0.38) ALDH1A1FFAR3MEN1CYP1A2THRB
SCHEMBL21269649 0.72 TSHR (0.38) ALDH1A1FFAR3MEN1CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492655-B2 Method of detecting a nucleic acid TORAY INDUSTRIES, INC. (JP) 2022-11-08 US disclosed
CN-114181223-A Cephalotaxine derivative and preparation method and application thereof 广州艾格生物科技有限公司 2022-03-15 CN disclosed
EP-3546590-A1 NUCLEIC ACID DETECTION METHOD Toray Industries, Inc. (JP) 2019-10-02 EP disclosed
US-20190276876-A1 METHOD OF DETECTING A NUCLEIC ACID TORAY INDUSTRIES, INC. (JP) 2019-09-12 US disclosed
WO-2019142480-A1 TEMPERATURE DETECTION INK, TEMPERATURE DETECTION INK INITIALIZATION METHOD, TEMPERATURE INDICATOR, AND ARTICLE MANAGEMENT SYSTEM 株式会社日立製作所 2019-07-25 WO disclosed
WO-2019142485-A1 TEMPERATURE DETECTION LABEL AND ARTICLE MANAGEMENT DEVICE USING SAME 株式会社日立製作所 2019-07-25 WO disclosed
EP-2480666-B1 COMPOSITIONS, METHODS, AND KITS FOR ISOLATING AND ANALYZING NUCLEIC ACIDS USING AN ANION EXCHANGE MATERIAL QIAGEN GAITHERSBURG INC (US) 2017-03-08 EP disclosed
US-20160375143-A1 MIKTO-ARM BRANCHED POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-12-29 US disclosed
US-9238809-B2 Compositions, methods, and kits for isolating and analyzing nucleic acids using an anion exchange material QIAGEN GAITHERSBURG, INC. (US) 2016-01-19 US disclosed
EP-2480666-A1 COMPOSITIONS, METHODS, AND KITS FOR ISOLATING AND ANALYZING NUCLEIC ACIDS USING AN ANION EXCHANGE MATERIAL QIAGEN Gaithersburg, Inc. (US) 2012-08-01 EP disclosed
US-5391818-A Tricarboxylic acid-functional monomers and polymers prepared from same THE SHERWIN-WILLIAMS COMPANY (US) 1995-02-21 US disclosed
US-5349080-A Ester-functional monomers and polymers prepared from same THE SHERWIN-WILLIAMS COMPANY (US) 1994-09-20 US disclosed
US-5328910-A Bradycardial agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-07-12 US disclosed
US-5225431-A Treatment of migraine BURROUGHS WELLCOME CO. (US) 1993-07-06 US disclosed
EP-0313397-B1 THERAPEUTIC HETEROCYCLIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1993-06-02 EP disclosed
EP-0231081-B1 HYDROXAMIC ACIDS ICI AMERICAS INC. (US) 1993-03-17 EP disclosed
EP-0482804-A1 Pyrrolo[2,3-d]pyrimidines with cardiovascular activity, process for their preparation and pharmaceutical compositions containing them ZENECA LIMITED (GB) 1992-04-29 EP disclosed
EP-0313397-A1 Therapeutic heterocyclic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1989-04-26 EP disclosed
US-4771038-A Hydroxamic acids ICI AMERICAS INC. (US) 1988-09-13 US disclosed
EP-0231081-A2 Hydroxamic acids ICI AMERICAS INC. (US) 1987-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160375143-A1 MIKTO-ARM BRANCHED POLYMERS MACO1, PCNA, IPO7 ALDH1A1 4643/4885FFAR3 2749/4885MEN1 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.