Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.75 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627175 | 0.90 | MAPK14 (0.62) | MAPK14MAPK11 | |
| Bms-582949 SCHEMBL254996 | 0.84 | MAPK14 (1.00) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL12729613 | 0.84 | MAPK14 (0.85) | MAPK14MAPK11CYP3A4 | |
| Bms-582949 SCHEMBL29554701 | 0.84 | MAPK14 (1.00) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL12728790 | 0.83 | MAPK14 (0.89) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL12779364 | 0.81 | MAPK14 (0.86) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL4412457 | 0.81 | MAPK14 (1.00) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL12729567 | 0.81 | MAPK14 (0.84) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL12779371 | 0.80 | MAPK14 (0.83) | MAPK14MAPK11CYP3A4 | |
| SCHEMBL12729693 | 0.80 | MAPK14 (0.77) | MAPK14MAPK11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160883-B2 | Pyrrolo-triazine aniline compounds useful as kinase inhibitors | BRISTOL-MYERS-SQUIBB COMPANY (US) | 2007-01-09 | — | — | US | disclosed |