Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 16/20 | 0.71 |
| ▸ | CDK9 | P50750 | 13/20 | 0.56 |
| ▸ | CCNK | O75909 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192322 | 0.88 | CCNT1 (0.69) | CCNT1CDK9CCNKPIM1PIM2 | |
| SCHEMBL1192916 | 0.83 | CCNT1 (1.00) | CCNT1CDK9CCNK | |
| SCHEMBL1461838 | 0.83 | CCNT1 (0.68) | CCNT1CDK9CCNK | |
| SCHEMBL12898647 | 0.83 | CCNT1 (0.82) | CCNT1CDK9CCNK | |
| SCHEMBL10179383 | 0.80 | CCNT1 (0.48) | CCNT1CDK9CCNK | |
| SCHEMBL1226139 | 0.80 | CCNT1 (0.48) | CCNT1CDK9CCNK | |
| SCHEMBL1463704 | 0.80 | CCNT1 (0.57) | CCNT1CDK9CCNK | |
| SCHEMBL1225532 | 0.80 | CCNT1 (0.52) | CCNT1CDK9PIM1PIM2 | |
| SCHEMBL1464131 | 0.79 | CCNT1 (0.46) | CCNT1CDK9 | |
| SCHEMBL12501629 | 0.79 | CCNT1 (0.46) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |