Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113913 | 1.00 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10112952 | 0.88 | HPGD (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10113025 | 0.88 | HPGD (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10113919 | 0.85 | POLB (0.54) | NPC1RAB9ASMN1; SMN2HPGDTP53 | |
| SCHEMBL10113912 | 0.81 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL14627796 | 0.81 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10133983 | 0.80 | HPGD (0.52) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10112954 | 0.80 | HPGD (0.52) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10113910 | 0.78 | PLK1 (0.48) | HPGDTP53EPHX1EPHX2CA12 | |
| SCHEMBL10113032 | 0.77 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | NPY5R, NPY1R, NPY2R | NPC1 1435/4885RAB9A 3699/4885SMN1; SMN2 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.