Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | HPN | P05981 | 5/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.40 |
| ▸ | HGFAC | Q04756 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | CAPN2 | P17655 | 8/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12214852 | 0.89 | HDAC3 (0.48) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL2185622 | 0.89 | HDAC3 (0.48) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL12214847 | 0.89 | HDAC3 (0.48) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL14627996 | 0.89 | TMPRSS2 (0.41) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL2700971 | 0.88 | F2 (0.44) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL2700973 | 0.88 | F2 (0.44) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL12214895 | 0.88 | HDAC3 (0.52) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL14628057 | 0.87 | HDAC3 (0.42) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL8258562 | 0.83 | HDAC3 (0.49) | TMPRSS2F2HPNST14HGFAC | |
| SCHEMBL12214918 | 0.78 | HDAC3 (0.46) | TMPRSS2F2HPNST14HGFAC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160854-B2 | Binaphthyl peptidomimetics for treating vancomycin resistant Staphylococcus aureas infections | UNIVERSITY OF WOLLONGONG (AU) | 2007-01-09 | — | — | US | disclosed |