Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.64 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.64 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.64 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083208 | 0.93 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083418 | 0.91 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081985 | 0.89 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083752 | 0.87 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2082966 | 0.87 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083025 | 0.87 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2617010 | 0.85 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083686 | 0.84 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2083913 | 0.84 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11DDR2 | |
| SCHEMBL2081728 | 0.83 | MAPK14 (0.78) | MAPK14MAPK13MAPK12MAPK11DDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008917-A2 | MODULATION OF PROTEIN FUNCTIONALITIES | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-01-18 | — | — | WO | disclosed |