Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 11/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956840 | 0.84 | ERN1 (0.74) | ERN1LCK | |
| SCHEMBL27258648 | 0.84 | ERN1 (0.74) | ERN1LCK | |
| SCHEMBL850871 | 0.82 | MAPT (0.59) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL2552977 | 0.81 | ERN1 (0.78) | ERN1PARP1 | |
| SCHEMBL11585526 | 0.80 | TYR (0.52) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL6766308 | 0.80 | ERN1 (0.50) | ERN1LCKPARP1PARP10PARP3 | |
| SCHEMBL15652760 | 0.78 | ERN1 (0.49) | ERN1LCKPARP1PARP10PARP3 | |
| SCHEMBL15652131 | 0.78 | ERN1 (0.55) | ERN1LCKPARP1PARP10PARP3 | |
| SCHEMBL18133064 | 0.77 | ERN1 (0.47) | ERN1LCKPARP1PARP10PARP3 | |
| SCHEMBL15493934 | 0.77 | ERN1 (0.48) | ERN1TYRTRIM24TRIM33PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1524268-B1 | Compounds and method for preparing sustituted 4-phenyl-4-cyanocyclohexanoic acids | SMITHKLINE BEECHAM CORP (US) | 2007-01-17 | — | — | EP | disclosed |