Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294623 | 0.81 | TSHR (0.37) | TSHRFAAHLMNAMEN1MAPK1 | |
| SCHEMBL7136990 | 0.79 | TSHR (0.34) | TSHRFAAHLMNAMEN1MAPK1 | |
| SCHEMBL6056313 | 0.78 | — | — | |
| SCHEMBL10915525 | 0.77 | TSHR (0.48) | TSHRFAAHLMNAKMT2A | |
| SCHEMBL9491466 | 0.76 | TSHR (0.47) | TSHRFAAHLMNAMEN1KMT2A | |
| SCHEMBL3675070 | 0.74 | TSHR (0.44) | TSHRFAAHLMNA | |
| SCHEMBL6748775 | 0.74 | TSHR (0.44) | TSHRFAAHLMNA | |
| SCHEMBL11787485 | 0.74 | CES1 (0.39) | TSHRFAAHMEN1KMT2A | |
| SCHEMBL27563912 | 0.74 | CES1 (0.39) | TSHRFAAHMEN1KMT2A | |
| SCHEMBL11787491 | 0.74 | CES1 (0.39) | TSHRFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2548639-B1 | Detection of process temperature anomalies in tubuar reactors | NOVA CHEM INT SA (CH) | 2015-09-09 | — | — | EP | disclosed |
| US-8755947-B2 | Roller detection | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2014-06-17 | — | — | US | disclosed |
| US-20130022498-A1 | Roller detection | NOVA CHEMICALS (INTERNATIONAL) S.A. | 2013-01-24 | — | — | US | disclosed |
| EP-2548639-A1 | Detection of process temperature anomalies in tubuar reactors | Nova Chemicals (International) S.A. (CH) | 2013-01-23 | — | — | EP | disclosed |