Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.54 |
| ▸ | CDK2 | P24941 | 10/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.54 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.54 |
| ▸ | CDK1 | P06493 | 6/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.54 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4832619 | 0.91 | MAPT (0.64) | MAPTMEN1LMNAKMT2ACCNA2 | |
| SCHEMBL14274180 | 0.88 | MAPT (0.59) | MAPTMEN1LMNAKMT2ACCNA2 | |
| SCHEMBL4836233 | 0.86 | MAPT (0.60) | MAPTMEN1LMNAKMT2ACCNA2 | |
| SCHEMBL14302722 | 0.79 | MAPT (0.48) | MAPTMEN1LMNAKMT2ACCNA2 | |
| SCHEMBL4829427 | 0.78 | GALR1 (0.59) | MAPTMEN1LMNAKMT2ACCNA2 | |
| SCHEMBL4838460 | 0.77 | MAPT (0.72) | MAPTMEN1LMNAKMT2AGAA | |
| SCHEMBL4873970 | 0.76 | MAPT (0.58) | MAPTMEN1LMNAKMT2AGAA | |
| SCHEMBL4837799 | 0.76 | GALR1 (0.55) | MAPTMEN1LMNAKMT2ACCNA2 | |
| SCHEMBL4829486 | 0.76 | MAPT (0.48) | MAPTMEN1LMNAKMT2AGAA | |
| Cyclohexane SCHEMBL4873977 | 0.74 | MAPT (0.82) | MAPTMEN1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169785-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-30 | — | — | US | disclosed |
| US-7163943-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-16 | — | — | US | disclosed |