Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | AHCY | P23526 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5694209 | 0.75 | GSK3B (0.61) | GSK3BALDH1A1ADORA2AADCY5EGFR | |
| SCHEMBL27352120 | 0.75 | GSK3B (0.69) | GSK3BAHCYALDH1A1ADORA2AADCY5 | |
| SCHEMBL29274097 | 0.74 | GSK3B (0.73) | GSK3BAHCYALDH1A1ADORA2AADCY5 | |
| SCHEMBL5694260 | 0.73 | GSK3B (0.56) | GSK3BAHCYALDH1A1ADORA2AADORA1 | |
| SCHEMBL9393670 | 0.72 | GSK3B (0.69) | GSK3BAHCYALDH1A1ADORA2AADCY5 | |
| SCHEMBL27599134 | 0.72 | GSK3B (0.69) | GSK3BAHCYALDH1A1ADORA2AADCY5 | |
| SCHEMBL8506354 | 0.72 | GSK3B (0.60) | GSK3BAHCYALDH1A1ADORA2AADORA1 | |
| SCHEMBL2346678 | 0.71 | GSK3B (0.67) | GSK3BAHCYALDH1A1ADORA2AADCY5 | |
| SCHEMBL16401533 | 0.71 | GSK3B (0.55) | GSK3BAHCYALDH1A1ADORA2AADORA1 | |
| SCHEMBL3630349 | 0.70 | GSK3B (0.65) | GSK3BAHCYALDH1A1ADORA2AADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2734211-A1 | ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | Medestea Research & Production S.p.A. (IT) | 2014-05-28 | — | — | EP | disclosed |
| EP-2734211-A1 | ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | Medestea Research & Production S.p.A. (IT) | 2014-05-28 | — | — | EP | disclosed |
| WO-2013011489-A1 | ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | MEDESTEA RESEARCH & PRODUCTION S.P.A. (IT) | 2013-01-24 | — | — | WO | disclosed |
| WO-2013011489-A1 | ADENINE DERIVATIVES HAVING IMMUNOMODULATING ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY | MEDESTEA RESEARCH & PRODUCTION S.P.A. (IT) | 2013-01-24 | — | — | WO | disclosed |