⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14292257 | 1.00 | — | — | |
| SCHEMBL2031050 | 1.00 | — | — | |
| SCHEMBL12168252 | 0.78 | — | — | |
| SCHEMBL852156 | 0.76 | — | — | |
| SCHEMBL852140 | 0.76 | — | — | |
| SCHEMBL852141 | 0.76 | — | — | |
| SCHEMBL7878899 | 0.76 | — | — | |
| SCHEMBL20249829 | 0.74 | — | — | |
| SCHEMBL18902734 | 0.74 | — | — | |
| SCHEMBL24254526 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2014044615-A1 | DIHYDROQUINOLINONE DERIVATIVES | NOVARTIS AG (CH) | 2014-03-27 | — | — | WO | disclosed |
| US-7163943-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2007-01-16 | — | — | US | disclosed |