Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MLNR | O43193 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9965473 | 0.87 | TSHR (0.54) | NSD2MAPTBRD4KMT2AALDH1A1 | |
| SCHEMBL9965478 | 0.86 | TSHR (0.46) | NSD2MAPTBRD4KMT2AALDH1A1 | |
| SCHEMBL10224761 | 0.85 | TSHR (0.45) | NSD2MAPTBRD4MLNRKMT2A | |
| SCHEMBL9965418 | 0.85 | HDAC3 (0.48) | NSD2MAPTMLNRALDH1A1TSHR | |
| SCHEMBL9965412 | 0.85 | MLNR (0.47) | NSD2MAPTMLNRKMT2AALDH1A1 | |
| SCHEMBL9965471 | 0.83 | DYRK1A (0.50) | NSD2MAPTBRD4MLNRKMT2A | |
| SCHEMBL10224856 | 0.79 | CHRM3 (0.50) | NSD2MAPTBRD4KMT2AALDH1A1 | |
| SCHEMBL9965383 | 0.79 | HCRTR1 (0.47) | NSD2MAPTBRD4KMT2AALDH1A1 | |
| SCHEMBL9965403 | 0.79 | CHRM3 (0.49) | NSD2MAPTBRD4ALDH1A1TSHR | |
| SCHEMBL9965410 | 0.78 | CHRM3 (0.50) | NSD2BRD4KMT2ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003934-A2 | 17BETA-HYDR0XYSTER0ID DEHYDROGENASE TYPE 3 (17BETA-HSD3 ) INHIBITORS | STERIX LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |